Livon Labs liposomal vitamin C supplement

What Are Some Liposomal Vitamin C Benefits?

Livon Labs Canada liposomal vitamin C supplement

Lypo Spheric vitamin C is no ordinary supplement.


It delivers more vitamin C to where it’s needed most because of its unique structure.


As a nutrient, vitamin C, or ascorbic acid, is one of the 50 essential nutrients you need every day for optimal health.


Vitamin C is best known for its role as a powerful antioxidant both within the blood and in tissues & cells throughout the body including the brain.


What is oxidation? Think of it this way. Oxidation is what happens to an apple core when it’s exposed to the air; it browns. Or when an iron nail is exposed to water and air; it rusts.


Oxidation of bodily structures like protein, fats, carbohydrates and even our DNA, found in all tissues and organs, increases inflammation and the risk for chronic degenerative diseases. Vitamin C helps to prevent this from happening by protecting you.


But vitamin C is only as good as it’s ability to be where it needs to be which is why lypospheric technology is arguably superior for delivery of nutrients. For more on this, read my other post on liposomal vitamin C. So if these formulations are absorbed and distributed throughout the body better, what are the liposomal vitamin C benefits?


Vitamin C molecule on a chalk board with a sliced orange - found in liposomal vitamin C


What Are The Benefits Of LypoSpheric Vitamin C?


Much of the vitamin C you take orally, either via food or supplements, isn’t absorbed by the gut. Smaller amounts are absorbed better, e.g. if you took 100 mg, you’d absorb about 98 mg. There is a larger fractional absorption amount.


The fractional absorption amount decreases though with larger doses. Only about 1000-1250 mg of vitamin C would be absorbed with a single 2000 mg dose. More total vitamin C is absorbed but it’s less efficient. To put this in perspective, a single 12,000 mg dose would only result in about 16%, or 1920 mg, of it being absorbed.


Pharmacokenetics of vitamin C.


Vitamin C must be transported through the gut wall using transporters. There are only so many transporters available and this action requires energy. Also, there only so much time before vitamin C moves along on its merry way down the digestive tract. Once vitamin C has moved on, its lost it chance to be absorbed. As you can see, there are limitations with the absorption of traditional vitamin C.


Being wrapped in essential phospholipids, the vitamin C is absorbed like dietary fats. It is taken up by the lymphatic system with an estimated 98% efficiency. Once there, it moves from the lymphatic system into bloodstream. Liposomes deliver more vitamin C into the circulation compared to traditional vitamin C supplements.


The circulating vitamin C-rich liposomes deliver more vitamin C to your tissues and organs. The liposomes bind to the cell membranes where they release vitamin C into the cell, effectively raising INTRA-cellular levels.


Liposomal-encapsulated Ascorbic Acid: Influence on Vitamin C Bioavailability and Capacity to Protect Against Ischemia–Reperfusion Injury


Source of essential phospholipids

It’s not just about the vitamin C. When you take liposomal products, you’re getting all the nutritional benefits of the material that the liposomes are made from. Liposomes are made of phospholipids with a high concentration of phosphatidyl-choline, which is a building block of all of your cellular structures including cell membranes.


It’s the unique phospholipid-based structure of liposomes that allows them to ‘slip’ through the cell membrane (without needing energy) and right into the cell where the vitamin C is needed, and can delivered efficiently.


Phospholipid with choline found in lypo spheric vitamin c


Phosphatidyl-choline is an essential phospholipid, a fatty acid that your body can’t produce on its own so you need to get it from food.


Phosphatidyl-choline is an essential structural component of the human body. Composed of phospholipids, the cell membrane is like the wall around a walled city. When the wall is damaged or breached, enemies can lay siege on the city. It’s the same way with your cells. A damaged membrane leaves the contents of your cells vulnerable. A steady supply of phospholipids can help to fill in the gaps in the cell wall fortification.


Phosphatidyl-choline is also a source of the much needed nutrient choline. Most people don’t get enough choline and its importance in human health has been somewhat lost. To learn more, read my post Choline. Always A Bridesmaid, Never A Bride.


Reproduces our hypothesized lost ability to synthesize our own vitamin C

Now, here’s where it gets really interesting. This concept will be new to most people.


Along with primates and guinea pigs, humans are the only other mammal on Earth incapable of making our own vitamin C. It’s true.


The Genetics of Vitamin C Loss in Vertebrates


 Goats, dogs, cats, elephants, pigs, horses and other mammals make their own vitamin C [in their livers and/or kidneys] and they make it in huge quantities. Much more on a per kg of body weight basis than what’s recommended for human health. Much, much more than the 90 mg or so per day recommended for adult humans.


But researchers say it wasn’t always like that. Our earlier ancestors used to make their own vitamin C.


Ridiculous Dietary Allowance – A Challenge to the RDA for Vitamin C


We’re missing the enzyme L-gulonolactone oxidase (GLO) needed to do this for ourselves. 


You and I have the gene in our DNA that’s responsible to make the GLO enzyme [and by extension vitamin C], but it’s mutated. Because of this, our liver cells can’t ‘read’ the gene and are unable to finish the final step of making vitamin C from glucose. Not only do we have all the other genes to make vitamin C, all of those genes are active in us except for the last one.


vitamin C synthesis from glucose

Photo credit


Note. In diagram above, you (mammals) have can do everything until the last step L-GulL to L-ascorbate “vitamin C”


What is vitamin C? How does it function biochemically? Why can’t humans synthesize it?


It’s for this reason that some think vitamin C [and the inability to make it] should be reclassified. That vitamin C production defects should be seen as an “inborn error of carbohydrate metabolism”.


Researchers theorize that once, long ago, we produced large amounts of vitamin C just like those animals that can make it themselves do. For example, a 150 or 72 kg goat can produce up to 13,000 mg of vitamin C per day. More when its under stress.


Homo sapiens ascorbicus, a biochemically corrected robust human mutant.


Animals that produce their own vitamin C do so all day long, 24/7. As a result, they have both higher levels of vitamin C in their blood and within their cells. A liposomal vitamin C benefit is one where it raises your INTRA-cellular (within the cell) levels of vitamin C like it would if you made your own vitamin C all day long. Like a goat.


Liposomal vitamin C benefits you by mimicking the hypothesized, long lost ability to maintain higher levels of vitamin C within your cells like they would have been when, like our ancestors. you made your own..


Liposomal vitamin C sachet - by Doug Cook RD

Better delivery of vitamin C to maturing white blood cells

Your immune system LOVES vitamin C. So do your adrenal glands. They selectively take up vitamin C from your blood stream and concentrate in their cells but I digress [hint, vitamin C helps with stress tolerance].


Vitamin C benefits your immune system too. It is the premier antioxidant circulating throughout the body but vitamin C does more. Studies have clearly established vitamin C’s ability to directly promote and stimulate a number of very important functions of the immune system.


These functions include the following:

  • Enhanced antibody production (B-lymphocytes, humoral immunity)
  • Increased interferon production
  • Enhanced phagocytic (scavenger cell) function
  • Improved T-lymphocyte function (cell-mediated immunity)
  • Enhanced B-lymphocyte and T-lymphocyte proliferation6. Enhanced natural killer cell activity (very important anti-cancer function)
  • Improved prostaglandin formation
  • Increased nitric oxide production by phagocytes


Can vitamin C reduce cold duration?


Phagocytic white blood cells (granulocytes) have 25X more vitamin C than what’s in the blood. Vitamin C is ‘used up’ when these cells digest pathogens and cellular “debris”. These cells are like PACMANs, moving about the body, gobbling up the bad guys.


The biggest consumer of vitamin C in the immune system though, are  the monocytes. These are also known as a macrophages; another cell with phagocytic functions. They are vitamin C hogs. Monocytes have more than an 80X increased concentration of vitamin C inside it relative to the blood.


Ascorbate – The Science of Vitamin C


Lypo spheric vitamin C benefits the immune system because of the structure of the liposome. Because it is absorbed as fat, lipsosomal vitamin C enters the lymphatic system where it is transported to the lymph nodes throughout the body.


Once there, the liposomes release the vitamin C into the maturing blood cells so that when released into the blood stream, are ‘super charged’, ready to fight the good fight and keeping your healthy.

Liposomal vitamin C pouring into a glass of water - by Doug Cook RD


Liposomal vitamin C side effects

Lypo spheric vitamin C is very well tolerated. There are no known meaningful liposomal side effects when reasonable doses are taken.


Safety studies have shown that 1 to 5 g per day are well tolerated. In studies where very large doses are taken, 20 – 30 g, some subjects experience some gastrointestinal upset.


This is thought to be due to the phospholipid content. Large intakes of fat can cause some gas, bloating and flatulence. Smaller doses spread out over the day is a good dosing pattern.


Doug Cook RDN is a Toronto based integrative and functional nutritionist and dietitian with a focus on digestive, gut, and mental health.  Follow me on FacebookInstagram and Twitter.

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