Liposomal vitamin C by Livon Labs - Doug Cook RD

Why Is Liposomal Vitamin C Better Than Regular Vitamin C?

Liposomal vitamin C by Livon Labs - Doug Cook RD

Vitamin C is probably one of the best known vitamins around.


Growing up, we always had a bottle on the kitchen table, conveniently found on the ‘lazy Susan’. We typically had chewable, orange-flavored tablets in either 250 mg or 500 mg dosages.


Taking one with breakfast, along with a multivitamin with minerals was just part of my family’s morning routine at breakfast.


My mother instilled the importance of good nutrition at an early age, whether she was aware of it or not, and the foundation for the proper use of nutritional supplements was also laid.

What is vitamin C?

Vitamin C, or ascorbic acid, is one of the 50 essential nutrients you need everyday for optimal health. Vitamin C is needed for collagen production. Collagen is an important structural proteins of the skin, tendons, bone, teeth, cartilage and all other connective tissues.


Vitamin C is needed for proper neurotransmitter production – compounds that help to regulate your mood. Vitamin C is best known as a powerful antioxidant both in the blood and in tissues & cells throughout the body including the brain.


Oxidation is what happens to an apple core when it’s exposed to the air; it browns. Oxidation of bodily structures like protein, fats, carbohydrates and even the DNA in your tissues and organs, increases inflammation and the risk for chronic degenerative diseases.


Vitamin C molecule on a chalk board with a sliced orange found in liposomal vitamin C


Vitamin C helps to prevent this from happening. It protects you from dangerous compounds that are generated during normal metabolism. Vitamin C also protects from the free radicals through exposure to toxins and pollutants.


These include first or second-hand smoke, exposure to, and the metabolism/breakdown of recreational and prescription drugs. Other toxins include alcohol, air pollution, inflammation from trans fats and diets high in sugar. You are also exposed to toxins produced by viruses, bacteria and other pathogens that your immune is faced with everyday.


Vitamin does vitamin C do?

  • Helps the body to metabolize fats and proteins.
  • A factor in energy production
  • Aids in the development and maintenance of bones, cartilage, teeth and gums.
  • Helps in connective tissue formation.
  • Helps in wound healing.
  • An antioxidant for the maintenance of good health.
  • Protects against free radicals and the damage & oxidative effects of free radicals
  • Helps to prevent vitamin C deficiency
  • Supports a healthy immune system & reduces the risk for chronic diseases
  • Supports collagen production for healthier skin, muscles and joints
  • Improves the appearance of skin; more supple, improved clarity [see details about skin study below]
  • A dietary antioxidant that significantly decreases the adverse effects of free radicals on normal physiological function & lipid oxidation in body tissues
  • Supports optimal overall health

* Health Canada approved health & function claims


Structure of liposomal Vitamin C


What are liposomes?

A liposome is a very tiny sphere comprised of a outer wall of fat and an inner payload of any of a number of water-soluble substances. Of particular interest is that the outer fat wall is made of the same fat that makes up the normal cell membranes throughout the body: phospholipids.


Because of this, liposomes have actually been studied as artificial models of cells. However, liposomes are vastly smaller than any of the cells in the body, allowing them to pass into the cells without difficulty.


What really makes the liposome so special is that can deliver its contents (nutrients) directly into the cells of the body without the consumption of energy. An added bonus, liposomes protect its contents from digestion or oxidation before the final delivery into the cells.


When a nutrient can be delivered into the cells of the body, not be degraded before delivery, and not consume energy in the process, the effects of that nutrient can be optimized in a way that even intravenous delivery often does not match. Liposomal vitamin C is great for that reason.


Liposomal vitamin C sachet - by Doug Cook RD


A recent clinical trial by world-renowned vitamin C expert and pharmacologist, Steve Hickey, PhD, showed that liposomal vitamin C was able to produce serum levels of vitamin C nearly double those thought theoretically possible with any oral form of vitamin C.


This astounding level of bioavailability not only dramatically increases the amount of vitamin C in the blood, but recent thermographic microscopy provides visible evidence that it also aids its entry into individual cells.


Even IV vitamin C has it’s limits in terms of raising intracellular levels of vitamin C because the vitamin C is still in the serum. It does easily pass into the cells. Studies estimate that only about 20% of the vitamin C from IV delivery gets into the cells despite very high concentrations in the serum. Liposomal C is different.


Vitamim C researcher Thomas Levy has found through years of clinical experience  that a much smaller oral dose of lypo spheric vitamin C (5 to 10 grams) often results in a similar clinical response than a much larger dose of vitamin C given intravenously (25 to 100 grams). 


Why is liposomal vitamin C better?

Regular vitamin C is an awesome all-purpose antioxidant. It does have a disadvantage. It is quickly absorbed, distributed throughout the circulation and then eventually filtered, and excreted by the kidneys.


Once taken, blood levels peak about 2 to 4 hours afterwards and then drift back down to pre-supplementation levels about 6-8 hours after that. If you want more from your regular vitamin C, several doses need to be taken throughout the day.


Some of the vitamin C will diffuse or be actively transported into the various cells of our body too like muscle, heart, kidney, liver, digestive tract, the brain, eyes etc.


It will offer antioxidant protection but the amount that gets into the cells is much less than the amount that’s in the blood stream outside the cell. Much of the vitamin C that doesn’t get into the cells will be excreted. This is why liposomes are better and lipospheric vitamin C offers greater benefits.


Cellular uptake of liposomes

Fluorescent microscopy  demonstrating increased absorption


Liposome encapsulation overcomes all these bioavailability and cellular uptake restrictions. Liposomes do not rely on specialized carrier transport system. Instead, due to their size and composition, they are able to passively absorb through the intestinal wall and through cellular membranes.


As a result, liposome-encapsulated nutrients (like Lypo Spheric Vitamin C and Liposomal Glutathione) provide a greatly enhanced bioavailability (delivery into the bloodstream) and greatly improved delivery into individual cells.


This is demonstrated in studies using fluorescent microscopy using LivOn Lab’s liposomal technology confirming passage of fluorescent dye-tagged containing liposomes across cellular membranes and into cultured cells.


This has the advantage of the vitamin C entering the lymphatic system first, giving up a lot of the vitamin C to the white blood cells of the immune system (those that love to concentrate vitamin C within their structures to fight infections and cancer such as the macrophages & phagocytes).


Here the vitamin C then enters the blood stream but unlike regular ascorbic acid that is filtered by the kidneys, when liposomal vitamin C is cleared from the blood it is taken up but the various cells, tissues and organs throughout the body. It it slips right through the cell membrane delivering lots of vitamin C into the cells and is not lost in the urine.


One form of vitamin C doesn’t, nor shouldn’t, replace the other. It’s best to have both forms to ensure maximum benefit!


Liposomal Vitamin C pouring into a glass of water


Study: Liposomal vitamin C improves skin quality

In a December 2014 study by Princeton Consumer Research Ltd., researchers conducted a double-blind placebo-controlled study to assess the impact of liposomal vitamin C on skin firmness and wrinkling.


Compared to placebo, those who took 1000 mg of lipospheric vitamin C per day saw a 35% increase in skin firmness and an 8% reduction in fine lines and wrinkles whereas those who took 3000 mg per day saw a 61% increase in skin firmness and a 14% reduction in fine lines and wrinkles.


The results are believed to be due to the fact that vitamin C is needed for the production of collagen and elastin, the skin’s supportive structural proteins, and that phospholipids are fats that make up all cell membranes.


Liposomes are the best way to deliver these nutrients into the skin cells. Liposomal vitamin C is the way to go.


To learn more watch this video What is Lypospheric (Liposomal) Technology?

Download the Vitamin C brochure

Purchase Lypo Spheric Vitamin C here


Doug Cook RDN is a Toronto based integrative and functional nutritionist and dietitian with a focus on digestive, gut, and mental health.  Follow me on FacebookInstagram and Twitter.

Comments 17

  1. Gwyn C Mountfield
    July 18, 2019

    You do not mention what type of Vitamin C you use. Do you use natural Vit C or Ascorbic Acid, which is synthetic Vit C, Chemically similar but nutritionally dissimilar. Would you clarify please.

    1. Doug Cook
      July 18, 2019

      Ascorbic acid is ascorbic acid…the biochemistry is the same. Ascorbic acid is the biochemical term for “vitamin C”. I have loads of papers on the pharmcokentics of ascorbate if you’re interested. Do you have papers to suggest otherwise? I’m always open to learning. Yes, ascorbic acid can be made from the isomerization of glucose but it’s used by the body in the same way…

      1. Old Dog
        August 20, 2019

        chemically its same, but ascorbic acid is produced artificially mainly through microbes and funghi. and 99% of all synthetic vitamin c comes from china.

        its chemically same but not pure. there are always little things from production which shouldnt be there like fungal spores or toxins.
        those certificates for purity only test a few things. they find only what they are searching for. its financially impossible to search for everything so you can consider those certs a scam.

        wanna see what happens when toxins come through even with clean vertificate? checkout the tryptophan scandal which killed thousands of people.

        1. Doug Cook
          August 20, 2019

          Thanks for your comments…I’m old enough to remember the isolated tryptophan issue…given the volume of supplements on the world stage, can you point me to the verified studies, reports and other to confirm what you’re saying? I’ve got a huge appetite for learning…awaiting the data…regards

  2. Glorya
    July 20, 2019

    nice article! This article can help me understand that vitamin C has many benefits
    Did you know that vitamin C can prevent cardiomyopathy due to Oxidative Stress Exposure? check here: prevent-kardiomiopati-akibat-pajian-stresor-oksidatif/

    thanks for sharing!

    1. Doug Cook
      July 20, 2019

      Not surprised, it’s such a potent, effective and universal antioxidant….!

  3. stan b
    September 26, 2019

    I take 20 ml. a day. How does that break down in dose terms . its in liposomal form. some days I take 2 doses. what is your opion of my regimen.

    1. Doug Cook
      September 26, 2019


      I use Livon Labs brand, so I don’t know about yours. The label should provide that information, re: your dose, it’s different for everyone. Basic maintenance is 1 g of vitamin C per day so whatever that is with your brand, that’s a good starting dose

  4. Robynne
    October 8, 2019

    How much Liv on liposomal Vitamin C can you take each day if you are dealing with Cancer? (2-4 packets a day?
    Are there any concerns regarding how much phosphatidylcholine you consume each day?

    1. Doug Cook
      October 8, 2019


      I can’t answer that actually, in terms of treatment but studies have used 10 g or more per day in general health – as way of general information, people routinely take 2 to 4 packets a day. The liposomes are just the same type of lipid found in human cells and 4 g of vitamin C is

    2. Doug Cook
      October 8, 2019

      Regarding the phospholipids, the amounts are minuscule compared to what you get in food

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